The center collaborates with a group of strategic partners to ensure the system's effectiveness and achieve its objectives. These partners include:

• Ministry of Commerce
• Ministry of Industry and Mineral Resources
• Ministry of Municipal, Rural Affairs, and Housing
• Ministry of Health
• Public Security (Traffic Department)
• Civil Defense
  
• Public Health Authority (Weqaya)
• Zakat, Tax, and Customs Authority
• Saudi Red Crescent Authority
• Consumer Protection Association
• Public Health Authority (Weqaya)
• Vehicle Safety Center​